Are Hemiplegic Migraines Hereditary
Migraine is a complex brain disorder explained by the interaction of genetic and environmental factors. In monogenic migraines, including familial hemiplegic migraine and migraine with aura associated with hereditary small-vessel disorders, the identified genes encode proteins expressed in neurons, astrocytes or vessels, which all increase the. There are three identified causal genes found in Hemiplegic Migraine – CACNA1A, ATP1A2 and SCN1A. Hemiplegic migraine is a rare type of migraine with aura caused by mutations in these genes. These genes influence how ion channels function, which has an impact on nerve activity.